Zero.53% report utilizing cocaine in the last 12 months. Zero.10% report utilizing methamphetamines. As much as zero.02% used heroin (knowledge is limited). 2.67% report misusing pain relievers. Eight.85% of all 12- to 17-year-olds used alcohol in the final month. They’re 3.29% less probably to make use of alcohol than the common American of their age group. 1.Sixty nine million 18- to 25-year-olds used drugs in the last month. 18- to 25-yr-olds in California are 18.24% extra doubtless to use medicine than the common American in the identical age group. 3.63% of teenagers aged 12- to 17-years-previous met the factors for IDUD within the last yr. 1.78% of teenagers aged 12- to 17-years-outdated met the factors for AUD in the last year.

An unmarked version of your revised paper with out tracked changes. You need to add this as a separate file labeled ‘Manuscript’. If you wish to make changes to your financial disclosure, please embrace your up to date assertion in your cowl letter. Pointers for resubmitting your figure recordsdata can be found below the reviewer comments at the top of this letter. We stay up for receiving your revised manuscript. When submitting your revision, we need you to address these extra requirements. 1. Please make sure that your manuscript meets PLOS ONE’s fashion necessities, together with those for регистрация фармацевтических субстанций file naming. [Note: HTML markup is beneath. 1. Does the manuscript present a valid rationale for the proposed research, with clearly recognized and justified analysis questions? The analysis question outlined is expected to address a valid academic drawback or topic and contribute to the bottom of knowledge in the sector. 2. Is the protocol technically sound and planned in a fashion that will result in a meaningful final result and allow testing the said hypotheses? 3. Is the methodology feasible and described in ample element to allow the work to be replicable?

Three.Forty eight% of all 12- to 17-year-olds met the standards for IDUD within the last 12 months. 1.57% of all 12- to 17-12 months-olds met the criteria for AUD in the last 12 months. Teenagers in Oklahoma are 10.10% less more likely to have used medication within the final month than the average American teen. Sixty one,000 or eleven.Eleven% of 12- to 17-year-olds report utilizing medication within the final month. Amongst them, 88.52% report using marijuana within the last month. 16.21% of all 12- to 17-year-olds report utilizing marijuana in the final 12 months. Zero.Fifty five% report using cocaine in the final yr. Zero.18% report utilizing methamphetamines. Up to 0.09% used heroin (information is limited). 2.55% report misusing pain relievers. Descriptions of methods and supplies in the protocol should be reported in sufficient detail for an additional researcher to reproduce all experiments and analyses. The protocol should describe the appropriate controls, sample measurement calculations, and replication wanted to ensure that the information are sturdy and reproducible. 4. Have the authors described the place all data underlying the findings will probably be made obtainable when the examine is complete?

123,000 adults aged 18- to 25-years-old used medication in the final month. 18- to 25-year-olds in Nevada are 10.55% more possible to use medicine than the average American in the identical age group. 4.70% of teenagers aged 12- to 17-years-previous met the standards for IDUD within the last yr. 1.71% of teenagers aged 12- to 17-years-previous met the factors for AUD within the final yr. They’re 8.64% extra likely to use alcohol than the common American of their age group. 129,000 adults aged 18- to 25-years-outdated used drugs in the last month. 18- to 25-12 months-olds in Louisiana are 22.27% much less doubtless to use drugs than the average American in the same age group. 2.49% of teenagers aged 12- to 17-years-previous met the criteria for IDUD within the final yr. Teenagers in Virginia are 16.Forty six% much less more likely to have used medicine in the final month than the common American teen. 44,000 or 6.96% of 12- to 17-12 months-olds report using medicine in the final month. Amongst them, 77.27% report using marijuana within the last month. 9.Sixty five% of all 12- to 17-year-olds report utilizing marijuana in the final year. Zero.32% report utilizing cocaine in the last 12 months. 0.Sixteen% report using methamphetamines. Up to 0.08% used heroin (information is limited).